In 145 CE, Rabbi Shimon bar Yochai hid in Tiberias for over a decade. He cleansed the city of ritual impurity. This enabled people to resettle in Tiberias
The Sanhedrin, the Jewish court fled from Jerusalem during the Great Jewish Revolt against the Roman Empire it finally settled in Tiberias around 150 CE. This was the Sanhedrin’s final meeting place. The Sanhedrin disbanded in the early Byzantine period.
From the time when Yochanan bar Nafcha settled in Tiberias, the city became the focus of Jewish religious scholarship in the land. The Mishnah along with the Jerusalem Talmud was compiled in Tiberias by Rabbi Judah HaNasi in around 200 CE.
13 synagogues served the spiritual needs of a growing Jewish population.